PANS/PANDAS in Down Syndrome


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Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) is a clinical diagnosis given to children who have a dramatic - sometimes overnight - onset of neuropsychiatric symptoms including obsessions/compulsions or food restriction.


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The core symptoms of PANS are OCD-like behaviors or restricted eating. Motor tics are also a symptom of PANDAS. In addition to more well-known OCD behaviors such as handwashing or counting, children may have obsessive thoughts about food. They may change their eating habits because of contamination fears, fears of choking, vomiting, or.


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PANDAS is a subtype of pediatric acute-onset neuropsychiatric syndrome (PANS). The main neuropsyciatric symptoms are the presence of obsessive-compulsive disorder (OCD) and/or tics (uncontrolled, sudden, repetitive movements or sounds), which are severe enough to interfere the ability to function.


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PANDAS is short for Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections. A child may be diagnosed with PANDAS when: Obsessive-compulsive disorder (OCD), tic disorder, or both suddenly appear following a streptococcal (strep) infection, such as strep throat or scarlet fever.


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Symptoms of PANDAS include: Acute onset (may be absent if onset was a long time ago) Obsessive compulsive behavior (often absent in patients with Down syndrome) Generalized anxiety Aggression, irritability, emotional lability Hyperactivity, restlessness Loss of speech (especially in Down syndrome) Hypersensitive to light and sound


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Moodiness, irritability, and crying or laughing at inappropriate times. Sensory problems, including being very sensitive to light and possibly seeing or hearing things that aren't there. Sleep.


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PANDAS syndrome is a group of mental health conditions that suddenly appear in a child after a strep infection. Learn about the causes, symptoms, and treatment.


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Overview What is PANDAS syndrome? PANDAS is short for "pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections." It describes a group of conditions thought to affect select children who've strep infections, such as strep throat or scarlet fever.


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The term 'PANDAS' is short for 'Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus' (The word streptococcus is often shortened to 'strep'). A child can be diagnosed with PANDAS when: Obsessive Compulsive Disorder (OCD) or tic symptoms suddenly appear for the first time, OR The symptoms suddenly get much worse, AND


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Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) syndrome is a childhood disorder that involves sudden changes in personality, behavior, and movement. It is caused by the immune system's overreaction to streptococcal (strep) infection, not the infection itself.


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We believe children who develop PANS or PANDAS have a genetic predisposition for these syndromes, which are triggered by an environmental stressor, often an infection. With PANS, that trigger is unknown. PANDAS is thought to be triggered by a Streptococcal infection. Blood tests conducted on children with PANS may show signs of inflammation.


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Since first defined in 1998 (), paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) and its later, broader iteration, paediatric acute-onset neuropsychiatric syndrome (PANS), have garnered significant attention and controversy.The role of streptococcal infection in children with explosive onset obsessive-compulsive disorder (OCD) and new onset.


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Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) is a childhood condition characterized by the sudden onset of obsessive-compulsive symptoms (OCD) and/or eating restrictions following a bacterial or viral infection, including COVID-19. These sudden changes often appear in combination with behavioral and neurological changes such as new.


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PANS (Paediatric Acute-onset Neuropsychiatric Syndrome) PANS is a neuropsychiatric condition which is triggered by a misdirected immune response to a variety of triggers, resulting in a constellation of symptoms as outlined below. PANS is a clinical diagnosis and there is no specific test which will prove or disprove the condition.


PANS/PANDAS in Down Syndrome

Help advocate for your loved one to get the right kind of treatment, especially if they are unable to communicate for themselves. Educate family members, your child's school, neighbors and healthcare providers through reliable sources. Find a list of medical professionals and support groups. Download our PANDAS Education Toolkit.


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While PANDAS/PANS is a lesser-known, often misdiagnosed disorder, providers play a key role in helping patients and families deal with this condition. We've collected some frequently asked questions for providers about diagnosis, treatment and more. How can PANDAS/PANS affect school participation?